12:00-19:00

Registration

15:00-17:30

Council of Physiology Professors     [Auditorium]

15:00-17:30

Young Physiologists meeting     [Aula San Francesco]

17:30-18:00

Opening Ceremony     [Auditorium]

18:00-19:00

Opening Lecture     [Auditorium]

Andrea Volterra (Lausanne, Switzerland)

Astrocytes in hippocampal memory and memory impairment

19:00

Welcome cocktail

20:00

Concert "UNE PETITE BARQUE"
viaggio per voce e pianoforte tra musica classica, contaminazioni etniche e jazz     [Auditorium]
Programme

08:30-09:50

Parallel Symposia

S1 • Active sensing: attention and motor planning     [Auditorium]
Chair: Rossella Breveglieri (Bologna, Italy)

Rossella Breveglieri (Bologna, Italy)

The medial posterior parietal cortex is a key node of attention for reaching

Paola Binda (Pisa, Italy)

Pupillometry gives a signature of implicit learning

Alessandro Benedetto (Florence, Italy)

The speed of visual processing changes with eccentricity: a combined EEG and behavioral investigation

Simona Monaco (Trento, Italy)

Possible role of attention in the early visual cortex during haptic exploration and motor planning

S2 • Environmental Stressors and Barriers dysfunction: assessing the impact on human health and diseases     [Aula A]
Chairs: Giulio Sancini (Monza, Italy) & Leonardo Ermini (Siena, Italy)

Giulia Terribile (Monza, Italy)

The impact of pollution on the neurovascular unit physiology

Cinzia Del Gaudio (Siena, Italy)

The effect of environmental stressors on the placenta barrier

Maria Chiara Valerii (Bologna, Italy)

Effect of microplastic exposure on intestinal homeostasis

Daniela Gaglio (Segrate, Italy)

Micro and nano plastics induce metabolic rewiring and signal transduction alteration in normal human colon cells: a risk factor for human health

S3 • Structure and function of ion channels from experiments and simulations     [Aula San Francesco]
Chair: Luca Maragliano (Ancona, Italy)

Anna Stary-Weinzinger (Vienna, Austria)

Allosteric mechanisms of inward rectifier K⁺ channel gating probed by disease mutants and ethosuximide

Arin Marchesi (Ancona, Italy)

Structural dynamics of membrane proteins by high-speed atomic force microscopy (HS-AFM)

Simone Furini (Cesena, Italy)

Atomistic simulations of C-type inactivation in potassium channels

Luigi Catacuzzeno (Perugia, Italy)

Building predictive Markov State Models of ion channel permeation from Molecular Dynamics

09:50-11:00

Parallel Oral Communications

Neurophysiology 1     [Auditorium]
Chairs: Anna Maria Aloisi (Siena, Italy) & Maria Vittoria Podda (Rome, Italy)

Giuseppe Aceto (Rome, Italy)

GPR158 activation decreases Kv7.2/KCNQ/M channel activity and increases intrinsic excitability in medium spiny neurons of the nucleus accumbens

Anna Maria Aloisi (Siena, Italy)

Establishment of a cellular model to investigate the role of the pain-insensitive ZFHX2 gene

Roberto Colangeli (Ancona, Italy)

"Tune the tone": The endocannabinoid system gates plasticity of tonic GABA inhibition

Laura Maggi (Rome, Italy)

Female mice exhibit similar long-term plasticity and microglial function at the ventral and dorsal hippocampal poles

Sara Martini (Rome, Italy)

Exploring the role of a chemogenetic LIMK1 analog in dendritic spine dynamics

Stefano Masoli (Pavia, Italy)

Filtering properties of a multicompartmental model of the cerebellar basket cell

Francesco Pastore (Rome, Italy)

Developing an inducible cAMP response element-binding protein (CREB) to control synaptic plasticity

Maria Vittoria Podda (Rome, Italy)

Brain complexity in stroke recovery after bihemispheric transcranial direct current stimulation in mice

Cellular Molecular and Muscle Physiology     [Aula A]
Chairs: Stefania Fulle (Chieti, Italy) & Andrea Marcantoni (Turin, Italy)

Martina Arici (Milan, Italy)

YAP1 plays a key role in human embryonic stem cell (hESC)-derived cardiomyocytes maturation

Elena Battirossi (Sesto Fiorentino, Italy)

Impact of β- and γ-actin Mutations Leading to Non-Muscle Actinopathies on Cell Cortex mechanics in Neurons

Matteo Moschetta (Milan, Italy)

Membrane-targeted photo-actuators for the light-dependent modulation of cell physiology

Luca Palloni (Milan, Italy)

AMPK is involved in the long-term regulation of the pacemaker current (I_f) by phosphorylating Ser1157 of HCN4 channels

Giuseppe Petito (Caserta, Italy)

Cannabinoid receptor type 1 deficiency triggers a complex adaptative response to improve gastrocnemius muscle function

Anna De Bartolo (Arcavacata di Rende, Italy)

Critical implications of the Fc region and FcγRIIA receptor in the side effects of Trastuzumab in human cardiomyocytes

Andrea Marcantoni (Turin, Italy)

Defining the effect of calcium released from ryanodine receptors on synaptic function

Physiology of Metabolism     [Aula San Francesco]
Chairs: Luisa Cigliano (Naples, Italy) & Sebastiano Banni (Monserrato, Italy)

Antonella Cano (Sassari, Italy)

Extracellular mass to body cell mass ratio (ECM/BCM) as predictor of nutritional, cognitive and functional status in elderly

Gianfranca Carta (Monserrato, Italy)

Novel nutritional insights on metabolic flexibility

Luisa Cigliano (Naples, Italy)

Modulation of gut-brain axis as a strategy to prevent western diet-induced cognitive dysfunction and stress response in rat hippocampus

Manuela Cipolletti (Rome, Italy)

A new link between metabolism and E2 signaling: involvement of PMM2

Anna Patrizia Gena (Bari, Italy)

Aquaporin-9 plays a role in the severe metabolic disorder and inflammation in a murine model of lysosomal acid lipase deficiency (LAL-D)

Giulia Querio (Orbassano, Italy)

GLUT4 membrane translocation in insulin-stimulated hiPSC-derived cardiomyocytes

Marianna Ranieri (Bari, Italy)

p-Coumaric acid prevented the vasopressin-induced water reabsorption through the activation of the Calcium-Sensing Receptor

Concetta Sozio (Naples, Italy)

Nutrient excess impairs osteoblast function through increased oxidative stress and impairment of DPP3/Nrf2 pathway

11:00-12:00

Poster Session 1 and Coffee break

12:00-13:00

Plenary Lecture     [Auditorium]

Inge Depoortere (Leuven, Belgium)

Tick-Tock: significance of circadian clocks in the gut

13:00-14:30

Lunch

14:30-15:50

Parallel Symposia

S4 • New insights into the role of protein post-translational modifications in brain plasticity and neurological diseases     [Auditorium]
Chairs: Salvatore Fusco (Rome, Italy) & Paul Fraser (Toronto, Canada)

Salvatore Fusco (Rome, Italy)

The role of aberrant protein S-palmitoylation in diet- and age-related cognitive decline

Laura Civiero (Padua, Italy)

Exploring 14-3-3 interactome perturbations in brain disorders

Claudia Colussi (Rome, Italy)

Histone deacetylase 4 regulates the balance of synaptic protein SUMOylation in health and disease

Paul Fraser (Toronto, Canada)

Small ubiquitin modifiers as therapies for neurodegenerative diseases

S5 • New and old mechanisms of bidirectional communication between the brain and other organs     [Aula A]
Chair: Giuseppina D'Alessandro (Rome, Italy)

Chiara Zurzolo (Paris, France)

α-Synuclein-induced autophagy dysfunction in neuronal cells contributes to tunneling nanotube (TNT)-mediated interaction with microglia

Diego Centonze (Rome, Italy)

High-fat diet drives glutamatergic synaptic damage by shaping the gut microbiota and T cell dynamics in multiple sclerosis

Stefano Garofalo (Rome, Italy)

Platelets-derived serotonin tunes fear memory in mice

Nunzio Iraci (Catania, Italy)

Cell-to-cell communication and neuroprotection: insights from astrocyte-derived extracellular vesicles in Parkinson's disease

S6 • Advances in the physiology of breath holding     [Aula San Francesco]
Chair: Anna Taboni (Brescia, Italy)

Matteo Paganini (Padua, Italy)

Effects of breath-hold diving on gas exchange and the respiratory system

Giovanni Vinetti (Bolzano, Italy)

Energy metabolism and energy cost of dynamic apnoea

Antonis Elia (Stockholm, Sweden)

Dietary manipulations and their effect on breath-holding

Anna Taboni (Brescia, Italy)

Blood pressure control during breath holding

15:50-17:00

Parallel Oral Communications

Cellular and Molecular Physiology 1     [Auditorium]
Chairs: Marco Fiocchetti (Rome, Italy) & Myriam Catalano (Rome, Italy)

Rosario Amato (Pisa, Italy)

Retinal cell resilience to metabolic stress: a putative role of thyroid hormone system

Valentina Brunetti (Pavia, Italy)

The mechano-sensitive Piezo1 channel promotes the release of nitric oxide and hydrogen sulphide by triggering global Ca²⁺ signals in the human cerebrovascular endothelial cell line hCMEC/D3 cells

Antonio Cibelli (Bari, Italy)

Astrocytes mechanosensitivity to fluid stress is mediated by Piezo1 channel

Marco Fiocchetti (Rome, Italy)

Functional role of secreted neuroglobin (NGB) in counteracting neurodegenerative-related cellular stress

Antonio Michelucci (Perugia, Italy)

Piezo1 is an essential player in the regulation of cell volume in human glioblastoma cells

Daniele Pensabene (Pesche, Italy)

BET proteins inhibition by JQ1 restores redox dyshomeostasis in a cellular model of Parkinson’s Disease

Andrea Saponaro (Milan, Italy)

Targeting the facilitatory effect of cAMP on HCN2 channel opening promote analgesic actions

Teresa Soda (Catanzaro, Italy)

Transient Receptor Potential Ankyrin 1 (TRPA1) mediates hydrogen sulfide-induced Ca²⁺ entry and nitric oxide release in human cerebrovascular endothelium

Neurophysiology 2     [Aula A]
Chairs: Marcello D'Amelio (Rome, Italy) & Roberto Piacentini (Rome, Italy)

Maria Conforti (Pavia, Italy)

Altered excitatory/inhibitory balance in the prefrontal cortex of the IB2 KO mouse model of autism: from neuronal excitability to cerebellar modulation in vivo

Marcello D'Amelio (Rome, Italy)

Disentangling dopaminergic deficits along Alzheimer's disease: from experimental models to patients

Antonio De iure (Rome, Italy)

Observation of levo-dopa-induced dyskinesias mediated by a wave of depolarization in the striatum

Mattia Lorenzo Di Francesco (Genoa, Italy)

Light-dependent inhibition of epileptic-like neuronal hyperexcitability by a photo-activated molecular switch

Paraskevi Krashia (Rome, Italy)

Transcranial Alternating Current Stimulation (tACS) at gamma frequency: an up-and-coming tool to slow-down Alzheimer’s Disease

Livia La Barbera (Rome, Italy)

Midbrain lesion drives hippocampal monoamine drop causing NLRP3-mediated neuroinflammation and Alzheimer’s disease-like deficits

Ada Ledonne (Rome, Italy)

Targeting ErbB receptors to rescue nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome

Gilda Loffredo (Rome, Italy)

Prefrontal-tDCS activates ventral tegmental area dopamine neurons and ameliorates hippocampal-related cellular, functional and behavioural deficits in a mouse model of Alzheimer’s Disease

Neurophysiology & Environmental Physiology     [Aula San Francesco]
Chairs: Darin Zerti (L'Aquila, Italy) & Elena Fabbri (Bologna, Italy)

Danilo Bondi (Chieti, Italy)

Network physiology of hypoxia during rest and isometric exercise

Giulio Sancini (Monza, Italy)

Danger in the air: how air pollution can affect brain’s physiology

Daniele Borzelli (Messina, Italy)

An explicit strategy affects muscle synergy recruitment during adaptation to virtual surgeries

Valentina Ferretti (Rome, Italy)

Control of Nesting behavior by PVN-CA2 oxytocin signaling

Jose Fernando Maya Vetencourt (Pisa, Italy)

Enriched environment enhances visual responses of the inner retina in early-stage retinitis pigmentosa

Marco Morrone (Sassari, Italy)

Anatomo-physiological basis of the cross-education effect: a preliminary study

Umberto Quartetti (Palermo, Italy)

The semantics of space: exploring semantic grounding in the right posterior parietal cortex

Darin Zerti (L'Aquila, Italy)

Mitochondrial involvement in retinal degeneration and the role of nanoceria in rescuing mitochondrial function

17:00-18:00

Poster Session 2 and Coffee break

18:00-19:00

Herlitzka Lecture     [Auditorium]

Michael Caplan (New Haven, CT, USA)

Renal epithelial cell structure: form, function and malfunction

08:30-09:50

Parallel Symposia

S7 • Computational methods and models for motor control     [Auditorium]
Chair: Antonella Maselli (Rome, Italy)

Mostafa Safaie (London, United Kingdom)

Preserved neural dynamics across animals performing similar behaviour

Francesca Sylos Labini (Rome, Italy)

Investigating the emergence of modular neuromuscular control of stepping in infants

Emmanuel Guigon (Paris, France)

An optimal control framework for the production of limb movements

Marta Russo (Rome, Italy)

Which model for interceptive actions?

S8 • Mechanisms of synaptic dysfunction in epilepsies     [Aula A]
Chairs: Gabriele Ruffolo (Rome, Italy) & Miriam Sciaccaluga (Perugia, Italy)

Mirte Scheper (Amsterdam, The Netherlands)

Impaired migration and maturation of SST+ GABAergic interneurons in tuberous sclerosis complex

Gabriele Ruffolo (Rome, Italy)

Dysregulation of GABAergic function linked to SST and SST+ interneurons in Tuberous Sclerosis Complex

Miriam Sciaccaluga (Perugia, Italy)

Striatal synaptic dysfunctions in a mouse model of Lafora disease

Barbara Bettegazzi (Milan, Italy)

Gene therapy strategies to rescue synaptic dysfunction in epilepsy

S9 • Modulation of hippocampal synaptic plasticity and memory     [Aula San Francesco]
Chair: Maria Rosaria Tropea (Catania, Italy)

Stefano Guglielmo (Pisa, Italy)

Episodic memory: from the hippocampal-entorhinal circuit to a distributed network

Maria Rosaria Tropea (Catania, Italy)

The cross-talk between Amyloid-β, α7 nicotinic acetylcholine receptors and cyclic nucleotides at the synapse: from physiology to Alzheimer’s Disease

Elisa Calcagno (New York, NY, USA)

Enhancing memory and synaptic plasticity through histone acetylation modulation: implications for Alzheimer's disease therapy

Domenica Donatella Li Puma (Rome, Italy)

A vicious circle among Interleukin-1β, Aβ and Tau affects synaptic function and memory

09:50-11:00

Parallel Oral Communications

Neurophysiology & Physiology of Organs and Systems     [Auditorium]
Chairs: Fabiola Paciello (Rome, Italy) & Francesca Grassi (Rome, Italy)

Germana Cappellini (Rome, Italy)

Development of adaptive locomotion in children with Cerebral Palsy

Edoardo Lecce (Rome, Italy)

The greater force exerted by dominant muscles is driven by a higher excitatory input to motoneurons at various contraction intensities

Francesca Montarolo (Orbassano, Italy)

Atm deficiency is associated with motor impairment and dysfunction of cerebellar circuitry in mice

Lala Chaimae Naciri (Milan, Italy)

Artificial intelligence allows for the automatic identification of taste fungiform papillae

Fabiola Paciello (Rome, Italy)

Altered brain networks and auditory dysfunctions in 3×Tg-AD mice underlying early noise-induced memory deficits

Mohammed Zeroual (Sassari, Italy)

Sensory afferents from the face modulate cortical sensorimotor integration with topographic specificity and influence face expressions recognition

Mariangela Centrone (Bari, Italy)

Tamoxifen impaired the lithium-induced increased cilium length and necroptosis reduction

Sergio Delle Monache (Rome, Italy)

Do visual and vestibular perceptual biases mutually compensate during the execution of a self-motion visuo-vestibular task?

Cellular and Molecular Physiology 2     [Aula A]
Chairs: Vincenzo Migliaccio (Fisciano, Italy) & Giuseppina D'Alessandro (Rome, Italy)

Amilcare Barca (Lecce, Italy)

Ab initio definition of a functional network involving transthyretin, carnosine and copper with (patho)physiological implications in the familial amyloid polyneuropathy (TTR-FAP) rare disease

Giovanna Bastari (Rome, Italy)

Function role of Neuroglobin trafficking in mitigating ER-stress response in human neuron derived-cells

Alessio Canovai (Pisa, Italy)

Targeting the urokinase-type plasminogen activator receptor system to improve visual function in the rd10 mouse model of retinitis pigmentosa

Angela Ferrulli (Bari, Italy)

Downregulation of vasopressin-AQP2 pathway explains the secondary NDI associated with cystinosis: in vivo and in vitro evidence

Vincenzo Migliaccio (Fisciano, Italy)

Protective effects of the extra virgin olive oil phenol compound hydroxytyrosol against palmitate-induced organelle stress and insulin resistance

Agnese Roscioni (Ancona, Italy)

Developmental and epileptic encephalopathy-associated mutations cause constitutive opening of the Kv7.2 channel inner pore gate

Simona Scorza (Bari, Italy)

Unveiling the role of primary cilia: insights into cAMP signaling dynamics and GPCR functionality using advanced imaging techniques

Grazia Tamma (Bari, Italy)

AI-based prospective repurposing investigations for the identification of new promising vasopressin V2 receptor ligands

Neurophysiology 3     [Aula San Francesco]
Chairs: Davide Ragozzino (Rome, Italy) & Cristian Ripoli (Rome, Italy)

Francesca Natale (Rome, Italy)

Neural stem cell-derived extracellular vesicles preserve brain plasticity in experimental models of metabolic and neurodegenerative disorders

Davide Ragozzino (Rome, Italy)

Time-dependent phenotypical changes of microglia drive alterations in synaptic transmission in acute hippocampal slices

Matteo Spinelli (Sassari, Italy)

High fat diet reduces hippocampal dendritic spine density by altering S-palmitoylation of synaptic proteins

Giulia Tomagra (Turin, Italy)

Patch-clamp and diamond micro-electrode arrays (μ-D-MEA) recordings to monitor the action of exogenous α-synuclein on dopaminergic neurons’ electrical activity and dopamine release

Alessandro Tozzi (Perugia, Italy)

Evaluating early synaptic changes in a model of synucleinopathy before overt behavioral alterations

Giulia Urone (Palermo, Italy)

New strategies to counteract dopaminergic degeneration: in vitro and in vivo neurotrophic properties of the first positive allosteric modulator for metabotropic glutamate receptor 3

Valeria Vacanti (Catania, Italy)

Blocking dopamine D3 receptors enhances hippocampal synaptic plasticity and memory via post-synaptic mechanisms

Francesca Vacca (Genoa, Italy)

A pH-sensitive closed-loop nanomachine to control hyperexcitability at the single neuron level

11:00-12:00

Poster Session 3 and Coffee break

12:00-13:00

Ruzzier Lecture     [Auditorium]

Britta Engelhardt (Bern, Switzerland)

The Brain Barriers maintain CNS Immune Privilege

13:00-14:30

Lunch

14:30-15:30

pH Lecture     [Auditorium]

David Sulzer (New York, NY, USA)

Music math and mind

15:30-16:00

Coffee break

16:00-19:00

SIF General Assembly     [Auditorium]

YRP 2024 Prizes

Gaia Giuriato (Verona, Italy)

Mitochondrial influence on performance fatigability: considering sex variability

Eleonora Pali (Pavia, Italy)

Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells

Serena Canzolino (Milan, Italy)

NOD-1 activation increases the spontaneous activity and the I(f) current of murine sinoatrial node cells and alters their response to sympathetic stimulation

20:00

Musei Capitolini private tour & cocktail at Terrazza Caffarelli
Logistic info

The three poster sessions are scheduled for Thursday, 12 September, from 11:00 to 12:00 (PS1) and from 17:00 to 18:00 (PS2) and for Friday, 13 September, from 11:00-12:00 (PS3).

Poster presenters are required to be available for discussion during their assigned session.

When preparing your poster please remember that the poster's maximum size is 90 x 120 cm, width x height.

Correct format...      Wrong format...

The scheduled times for placement, presentation and removal of posters are:
PS1 (12/09/24): placement 8:30-11:00 am, presentation, 11:00-12:00, removal until 13:00.
PS2 (12/09/24): placement 13:30-17:00, presentation 17:00- 18:00, removal until 19:00.
PS3 (13/09/24): placement 8:30-11:00, presentation 11:00 - 12:00, removal until 13:00.

• Poster Session 1 Session 1 1
• Poster Session 2 Session 2 2
• Poster Session 3 Session 3 3

• Poster Session 1 • 12 September • 11:00-12:00

  Neurophysiology

  P1.1 Natalia Abate (Naples)
  Identifying Cystatin B interactors in brain cortex development to elucidate molecular mechanisms underlying EPM1 pathogenesis
  
  P1.2 Miriam Acquafredda (Rome)
  Ocular dominance plasticity in the adult brain: beyond short-term changes? Insights from 7t bold responses in amblyopic patients
  
  P1.3 Giulia Arena (Rome)
  A cell assembly-based strategy for whole brain interrogation of inter-regional coordination
  
  P1.4 Pietro Baldelli (Genoa)
  Glycolytic inhibition: an approach toward epigenetic control of neuronal excitability
  
  P1.5 Bernadette Basilico (Rome)
  Acute gut dysbiosis induces alterations in neuronal network excitability and triggers neuroinflammation in the brain
  
  P1.6 Danilo Benozzo (Pavia)
  Modeling the autistic cerebellum: propagation of granule cells alteration through the granular layer microcircuit
  
  P1.7 Elena Bossi (Varese)
  The sodium and GABA affinity determines the dual role of Betaine on GABA transport (GAT1)
  
  P1.8 Daniele Bottai (Milan)
  Does curcumin act as an antioxidant in neural stem cells in health and disease?
  
  P1.9 Ludovica Maria Busdraghi (Rome)
  GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis
  
  P1.10 Giuseppe Busetto (Verona)
  Action potential-mediated metaplasticity of excitatory synapse LTP
  
  P1.11 Federica Campanelli (Rome)
  Voluntary intensive exercise: neuroprotective effects on striatal functions of parkinsonian α-syn mice model
  
  P1.12 Diletta Capobianco (Bari)
  PTBP1 controls self-renewal of human neural stem cells and localizes inside tunneling nanotubes
  
  P1.13 Giulia Carozza (L'Aquila)
  Functional role of L-DOPA to promote melanogenesis and homeostasis of retinal pigment epithelial cells
  
  P1.14 Myriam Catalano (Rome)
  Microglia-released extracellular vesicles counteract age-related cognitive impairment and restore microglia homeostasis in aged male and female mice
  
  P1.15 Emma Cauzzi (Rome)
  Sulfavant A: a small marine-derived sulfolipid aids neuroprotection and reduces memory deficits in Tg2576 mouse model of Alzheimer’s disease
  
  P1.16 Imma Ceriello (Rome)
  Directional variations in muscle coordination during functional reach
  
  P1.17 Marta Cerina (Milan)
  β2-containing neuronal nicotinic receptors (nAChRs) in neocortex development and sleep-related epilepsy
  
  P1.18 Giuseppe Chiantia (Turin)
  Sub-toxic doses of glyphosate impair GABAergic synapses in cultured hippocampal neurons
  
  P1.19 Sara Cupini (Genoa)
  Platinum nanozymes counteract photoreceptor degeneration and retina inflammation in a light-damage model of age-related macular degeneration
  
  P1.20 Chiara D'Amelio (Rome)
  Transcranial Direct Current Stimulation ameliorates cognitive and depressive symptoms in a mouse model of ischemic stroke
  
  P1.21 Chiara D'Antoni (Rome)
  Rebalancing Neuronal Activity in 2D and 3D human iPSC based Fragile X disease models modulating the adenosine system
  
  P1.22 Eleonora Daghini (Pisa)
  The retina – a window on amyotrophic lateral sclerosis
  
  P1.23 Riccardo Dalla Volta (Milan)
  Early suppression of corticospinal excitability during the observation of pictures of hand actions
  
  P1.24 Marialaura De Grazia (Pavia)
  A Multi-Scale Virtual Mouse Brain for investigating cerebellar-related ataxic alterations
  
  P1.25 Maria Egle De Stefano (Rome)
  Duchenne Muscular Dystrophy affects peripheral innervation: observations on the sensory-motor sciatic nerve
  
  P1.26 Claudio Del Percio (Rome)
  Patients with neurodegenerative diseases show poor reactivity of posterior EEG alpha rhythms during the transition from eyes-closed to -open condition
  
  P1.27 Marta Delconti (Novara)
  Paclitaxel acutely activates I_CRAC in sensory neurons: implications for paclitaxel-induced peripheral neuropathy
  
  P1.28 Simona Denaro (Catania)
  Unveiling the potential of PARP1 and Connexin 43 modulation in neuropathic pain models
  
  P1.29 Franca Deriu (Sassari)
  A TMS and TMS-EEG study for the investigation of the transcallosal connections of face and hand representation areas in the primary motor cortex
  
  P1.30 Silvia Di Angelantonio (Rome)
  Neurodevelopmental and neurodegenerative effects of MAPT IVS 10+16 mutation in 2D and 3D human iPSC-derived cultures
  
  P1.31 Maria Amalia Di Castro (Rome)
  Interleukin-15 alters hippocampal synaptic transmission and impairs episodic memory formation in mice
  
  P1.32 Fabrizio Di Giovanni (Palermo)
  Spatial semantics is grounded in visuospatial perception: evidence from tDCS modulation of the right posterior parietal cortex in a lexical decision task in a virtual reality environment
  
  P1.33 Valentina Di Liberto (Palermo)
  Influence of lifestyle factors on episodic migraine: focus on dietary habits, physical activity, sleep, and stress management
  
  P1.34 Stefano Di Marco (Genoa)
  Shifting the focus from vascular to neuronal aspects in diabetic retinopathies to enable alternative treatment strategies such as dietary supplementation with Saffron Repron®
  
  P1.35 Francesco Di Palma (Bari)
  Development of 2D and 3D models for studying intercellular communication mediated by tunneling nanotubes in the hypoxic glioma microenvironment
  
  P1.36 Marianna Dionisi (Genoa)
  REST-dependent homeostatic control of neuronal hyperactivity induced by neuroinflammation
  
  P1.37 Chiara Feroleto (Rome)
  Human bone-marrow mesenchymal stem cell-derived extracellular vesicles, intranasally delivered, rescue motor deficits and promote tissue repair in a mouse model of cortical stroke
  
  P1.38 Maria Grazia Ferraro (Naples)
  FPR-2 as a potential game-changer for treating human malignant glioblastoma
  
  

  Cellular and Molecular Physiology

  P1.39 Filippo Acconcia (Rome)
  Characterization of ERα signaling to cell proliferation induced by chronic and pulsatile E2 stimulation in 2D and 3D cell cultures
  
  P1.40 Rosanna Avola (Enna)
  Essential oil from Origanum vulgare displays anti-inflammatory and healing activity on human keratinocytes
  
  P1.41 Pasquale Bianco (Sesto Fiorentino)
  Exploring Cell Mechano-transduction with Dual Laser Optical Tweezers
  
  P1.42 Francesca Bianco (Turin)
  Molecular mechanism of Br-SQ-C4 phototoxicity: the role of Ca²⁺ and ROS interplay
  
  P1.43 Gregorio Bonsignore (Alessandria)
  ER stress, honey and keratinocytes
  
  P1.44 Valeria Calabrese (Rome)
  Effect of Mitochondrial Complex I Inhibitor Rotenone on dopamine release and cell survival
  
  P1.45 Serena Calamaio (San Donato Milanese)
  Cardiotoxicity of proteasome inhibitors in multiple myeloma: differential effects of bortezomib and carfilzomib on calcium dynamics in hiPSC-derived cardiomyocytes
  
  P1.46 Beatrice Campanelli (Ancona)
  Characterization of new class of membrane targeted photo actuators through molecular dynamics simulations
  
  P1.47 Rosa Cardone (Bari)
  Extracellular acidosis drives pancreatic Vasculogenic Mimicry via Na⁺/H⁺ exchanger isoform 1 (NHE1) and calcium entry
  
  P1.48 Federica Coppola (Siena)
  Hypoxia-induced adaptive strategies: involvement of autophagy and sequestosome-1/p62 in human dendritic cells
  
  P1.49 Marika Cordaro (Messina)
  Molecular and cellular pathways contributing to brain aging: focus on isothiazolinone
  
  P1.50 Beatrice Corradi (Genoa)
  Envisioning the structural foundations for sodium channel Nav1.2 modulation by PRRT2
  
  P1.51 Arianna Cuomo (Caserta)
  Mitochondrial function in Amyotrophic Lateral Sclerosis caused by the pG376D TARDBP Mutation
  
  P1.52 Roberta De Zio (Bari)
  P2X7 receptor activation suppresses cell migration and induces membrane hyperpolarization in kidney renal clear cell carcinoma
  
  P1.53 Angela Di Battista (Perugia)
  Astrocyte-derived small extracellular vesicles hinder glioblastoma malignancy
  
  P1.54 Ilaria Di Gregorio (Fisciano)
  Protective effects of plant-derived matrices extracts against fatty acids-induced hepatic steatosis in Hepg2 cells
  
  P1.55 Lorenza Di Marsico (Pisa)
  β3-adrenoceptor role in hypoxia-driven retinal neovascularization: insights from the mouse model of oxygen-induced retinopathy
  
  P1.56 Annarita Di Mise (Bari)
  Combination of metformin and cinacalcet slows cystogenesis in human cysts obtained from an ADPKD patient through activation of the AMP-activated protein kinase (AMPK)
  
  P1.57 Alessandro Falsini (Siena)
  Highlighting the relevance of Carbonic Anhydrases in cell migration under hypoxia
  
  P1.58 Irene Filippi (Siena)
  Metabolic reprogramming and Hedgehog pathway in myeloid lineages under hypoxic conditions
  
  P1.59 Bernard Fioretti (Perugia)
  Voltage dependent potassium currents in human granulosa cells from follicular fluid of IVF of poor and normal responder patients
  
  

  Environmental Physiology

  P1.60 Teresa Balbi (Genoa)
  Physiological responses of early developmental stages of Mytilus galloprovincialis to ocean warming and pathogen infection in a global change scenario
  
  P1.61 Maria Carmela Cerra (Arcavacata di Rende)
  Exploring the functional effects of the ACE inhibitor Enalapril and its metabolite Enalaprilat on Mytilus galloprovincialis
  
  P1.62 Federica Impellitteri (Messina)
  Understanding benzisothiazolinone's impact on aquatic organisms: insights into physiological and cellular responses
  
  P1.63 Maria Assunta Iovine (Naples)
  Physiological response to seasonal variation in gills and digestive gland of Mytilus galloprovincialis
  
  P1.64 Tadeja Jakus (Izola, Slovenia)
  Exploring taste sensitivity in varied dietary patterns
  
  P1.65 Maria Giulia Lionetto (Lecce)
  Motility of Mytilus galloprovincialis hemocytes: a novel approach for detecting cellular responses to the exposure to emerging pollutants
  
  P1.66 Adriana Petito (Naples)
  Goldfish redox homeostasis adaptation to hypoxia
  
  P1.67 Maria Grazia Zizzo (Palermo)
  The “ELPME” project:  in vitro, ex vivo and in vivo studies for the evaluation of the effects of low dose exposure to mixture of pollutants in the onset of inflammatory bowel disease (IBD)
  
  

• Poster Session 2 • 12 September • 17:00-18:00

  Neurophysiology

  P2.1 Anthony Frosio (San Donato Milanese)
  Dopaminergic neurons derived from hiPSCs in multiple system atrophy exhibit distinct morphological and functional characteristics compared to healthy controls
  
  P2.2 Sergio Fucile (Rome)
  Spontaneous GABAergic synaptic currents are modulated by α4β2* nicotinic acetylcholine receptors in human epileptic brain
  
  P2.3 Alessandro Gaeta (Rome)
  Targeted over-expression of multiple GABA_A receptor subunits increases the sensitivity to GABAergic anti-seizure medications
  
  P2.4 Veronica Ghiglieri (Rome)
  Inhibitory transcranial magnetic stimulation reduces side effects of chronic Levodopa in experimental parkinsonism
  
  P2.5 Cecilia Giacomet (Rome)
  Age dependent alterations in cortico striatal synaptic plasticity of transgenic mice expressing neuromelanin
  
  P2.6 Stefano Grasso (Rome)
  Neural processes underlying motor control and decision making when acting with others
  
  P2.7 Ezia Guatteo (Naples)
  Functional and morphological alterations in mouse locus coeruleus noradrenergic neurons expressing neuromelanin granules 
  
  P2.8 Lorenzo Guidotti (Pisa)
  Morpho-functional alterations and miRNome dysregulation in the retina of a mouse model of Alzheimer’s disease: paving the way for new strategies of gene therapy
  
  P2.9 Arianna Ioni (Rome)
  BTK inhibitors modulate remyelination in Multiple Sclerosis
  
  P2.10 Ebrahim Ismaiel (Parma)
  Neural fingerprints of grasping actions in the monkey premotor cortex in head-fixed, head-free, and freely moving contexts
  
  P2.11 Giuliana La Rosa (Naples)
  Dual dose-dependent effects of palmitic acid (PA) on viability and maturation of Human Oligodendrocytes
  
  P2.12 Alessandra Laffi (Bologna)
  Effect of exercise training on postural control in people with diabetes
  
  P2.13 Roberta Lizio (Rome)
  Sex affects resting-state electroencephalographic rhythms in patients with dementia due to Parkinson’s and Lewy body diseases
  
  P2.14 Nicola Loi (Sassari)
  Correlation between cortical plasticity and cognitive skills in aged subjects
  
  P2.15 Susanna Lopez (Rome)
  Default mode network and posterior resting-state electroencephalographic alpha rhythms in Alzheimer’s disease patients
  
  P2.16 Francecso Mainardi (Pavia)
  Role of cerebellar network excitability and plasticity in the pathophysiology of dystonia
  
  P2.17 Giulia Mantero (Genoa)
  Conjugated polymer nanoparticles rescue vision loss in a mice model of retinal degeneration
  
  P2.18 Francesco Marrocco (Rome)
  The gut-brain axis: the role of the microbiota as a mediator of the enriched environment
  
  P2.19 Davide Martelli (Bologna)
  Manipulating the sympathetic mediated inhibition of immunity to prevent the development of health-care associated infections
  
  P2.20 Francesca Massenzio (Bologna)
  Microglia across neurodegenerative diseases: role of EVs-miRNA in neuroinflammation
  
  P2.21 Letizia Mazzarella (Rome)
  Natural Killer cells modulate peri-tumoral neuron activity in Glioblastoma
  
  P2.22 Giacomo Mazzoni (Genoa)
  A key molecular regulator of neuronal excitability and network stability: the interaction between PRRT2 and Nav1.2
  
  P2.23 Martina Montanari (Rome)
  Characterization of mitochondrial dysfunction and therapeutic potential of Nrf2 modulation in early-stage Parkinson’s Disease using Pink1^-/-mice
  
  P2.24 Anita Monteverdi (Pavia)
  Virtual brain simulations unveil hidden physiological parameters regulating network dynamics in dementia
  
  P2.25 Lisastella Morinelli (Genoa)
  TMEM151A, a new causative gene in Paroxysmal Kinesigenic Dyskinesia
  
  P2.26 Alessandro Mormino (Rome)
  Natural Killer cells prime the synaptic pruning by microglia necessary for normal memory formation
  
  P2.27 Marta Morotti (Rome)
  Brain structural and functional connectivity biomarkers for early detection of alzheimer’s disease
  
  P2.28 Giulia Puliatti (Rome)
  Lithium-charged gold nanoparticles: a new tool for the in vitro and in vivo modulation of Glycogen Synthase Kinase 3
  
  P2.29 Cristiana Roberta Multisanti (Messina)
  Exploring basal locomotor activity and light-off visual-motor response in zebrafish larvae: influence of age, time of the day, and biological replicates
  
  P2.30 Ida Nifo Sarrapochiello (Rome)
  Chronic exposure to low doses of benzene affects cognitive functions through the alteration of molecular mechanisms underlying brain plasticity 
  
  P2.31 Giuseppe Noce (Naples)
  Cortical neural synchronization mechanisms are abnormal in patients with dementia due to Parkinson's and symptomatic Huntington's diseases
  
  

  Muscle Physiology

  P2.32 Roberto Bonanni (Rome)
  Muscle cell responses to a pan agonist of estrogen receptor-related receptors: an in vitro study of exercise physiology
  
  P2.33 Elisabetta Catalani (Viterbo)
  Translational potential of a new synthetic Sirtuin1-activating compound to rescue muscle performance and phenotypes in Duchenne Muscular Dystrophy
  
  P2.34 Federica Geddo (Turin)
  Insulin-mimetic role of S-Allyl cysteine in C2C12 myotubes
  
  P2.35 Mihaela Jurdana (Izola, Slovenia)
  Identification of sarcopenic obesity in adults undergoing orthopaedic surgery: Relationship between “a body shape index” (ABSI) and fat-free mass
  
  P2.36 Martina Parrella (Rome)
  Changes in the spatial distribution of lumbar erector spinae activity are associated with force steadiness variation during sustained task
  
  P2.37 Giusy Pietrafesa (Potenza)
  The microtubules plus-end tracking proteins CLIP-170 mediates nuclear shape in Emery-Dreifuss muscular dystrophy
  
  P2.38 Massimo Reconditi (Sesto Fiorentino)
  The dependence on the afterload of the degree of thick filament activation in the heart
  
  

  Cellular and Molecular Physiology

  P2.39 Chiara Florindi (Milan)
  Unveiling the biophysical mechanism of cardiomyocyte excitation-contraction coupling modulation by a membrane-targeted photoswitch
  
  P2.40 Sabino Garra (Bari)
  Selective inhibition of two aquaporin membrane channels, AQP3 or AQP9, impairs human PBMCs and neutrophil cell migration
  
  P2.41 Anna Gervasi (Catania)
  Intercellular communication regulates mitochondrial Cx43 trafficking in astrocytes and glioma cell lines 
  
  P2.42 Maria Elena Giordano (Lecce)
  Effect of the exposure to a polyethylene terephthalate nanoplastics model (PET) on murine NHI-3T3 fibroblast cells
  
  P2.43 Maria Vittoria Leonardi (Perugia)
  SARS-CoV-2 ORF3a protein is a water permeable channel that induces lysosomes swelling
  
  P2.44 Francesco Lodola (Milan)
  Mechanistic insights into estradiol-induced arrhythmias in long QT syndrome type 2
  
  P2.45 Martina Lucchesi (Pisa)
  Hypoxia-dependent upregulation of VEGF relies on β-adrenoceptor 3 signaling in endothelial and Müller cells: implications for ROP disease
  
  P2.46 Michele Maffia (Lecce)
  Copper overload affects α-synuclein clearance mechanisms in a Parkinson's disease in vitro model
  
  P2.47 Rosanna Mallamaci (Bari)
  Bergamot essential oil (BEO) provides cytoprotection in neuronal cells exposed to heavy metals
  
  P2.48 Rosa Mancinelli (Chieti)
  Myogenic precursor cell-derived extracellular vesicles: role in sarcopenia
  
  P2.49 Giuliana Mannino (Messina)
  Pericyte-like differentiated adipose-derived mesenchymal stem cells improve blood-retinal barrier preservation
  
  P2.50 Angela Marino (Messina)
  Anion exchanger 1/AE1 function is compromised in red blood cells from pre-diabetic subjects: beneficial effects of finger lime (Citrus australasica, Faustrime cultivar) juice extract
  
  P2.51 Silvia Marracci (Pisa)
  A preliminary study on the functional involvement of adrenoceptors in glioblastoma growth
  
  P2.52 Simona Martinotti (Alessandria)
  Cell surface GRP78: the dark side of glucose-regulated protein 78
  
  P2.53 Aurora Mazzei (Lecce)
  Differential cross-talk pathways of immune cells in co-culture with enterocyte-like monolayer challenged by apical vs. basolateral LPS exposure
  
  P2.54 Daniela Meleleo (Foggia)
  Role of calcium ion and anionic phospholipids on the ubiquitin aggregation process
  
  P2.55 Dario Melgari (San Donato Milanese)
  Autoimmune mechanisms in Brugada syndrome: plasma effects on Nav1.5 activity in HEK cells and hiPSC-derived cardiomyocytes
  
  P2.56 David Molla (Milan)
  A study of the negative and positive dominance of heterozygous Na_V1.5
  
  P2.57 Sara Monaci (Siena)
  The Hippo pathway as a novel regulator of dendritic cell physiology under hypoxia
  
  P2.58 Rossana Morabito (Messina)
  Aging-related oxidative stress impairs cellular shape function and signaling in human erythrocytes: Açaì berry is a keystone?
  
  

  Physiology of Organs and Systems

  P2.59 Tommaso Angelone (Arcavacata di Rende)
  Selenoprotein T as a novel key player in aging-associated myocardial dysfunction
  
  P2.60 Sara Baldassano (Palermo)
  A pilot study for preventing  minerals deficiency in the adult population by functionalized Seaweed Extract lettuce
  
  P2.61 Luana Vittoria Bauso (Messina)
  Physiological response of human osteoprogenitor cells on 3D-printed polymeric scaffolds for bone tissue regeneration
  
  P2.62 Marta Borrelli (Milan)
  The effect of cigarette smoking on the cardiorespiratory and metabolic kinetics in young physically active males
  
  P2.63 Maira Certini (Bari)
  Exploiting partial reprogramming to rejuvenate Drosophila melanogaster: a novel approach to assess the role of intestinal stem cells on age-dependent degradation of the intestinal barrier
  
  P2.64 Arianna Mazzoli (Naples)
  Diet-induced impairment of skeletal muscle and adipose tissue metabolic homeostasis and its prevention by probiotic administration
  
  P2.65 Eleonora Solari (Varese)
  Impact of intraluminal valves on hydraulic resistance and lymph flow in lymphatic collectors
  
  P2.66 Giorgia Sollai (Monserrato)
  Do humans perceive the odor of fatty acids by an orthonasal pathway?
  
  P2.67 Giovanna Traina (Perugia)
  Antioxidant role of bovine colostrum in a colitis murine model
  
  

• Poster Session 3 • 13 September • 11:00-12:00

  Neurophysiology

  P3.1 Paolo Flace (Bari)
  Morphofunctional study of serotonergic neurons in the adult human cerebellum
  
  P3.2 Salvatore Novello (Padua)
  The novel E83Q SNCA mutation drives specific protein handling, interactors and disease-phenotypes
  
  P3.3 Pierpaolo Pani (Rome)
  Changes in pupil responses precede behavioral adjustment in a rewards stop-signal task  
  
  P3.4 Roberto Panichi (Perugia)
  Optimized sensorimotor activation enhances real-time visuomotor coordination in goal-directed aiming
  
  P3.5 Virginia Papagni (Rome)
  Evidence for joint action awareness in macaque monkeys
  
  P3.6 Silvia Pascarella (Naples)
  Effect of early life stress on cerebellar development
  
  P3.7 Ann Paul (Rome)
  Evidence of EEG correlates of memory-based decision-making during a  transitive inference task
  
  P3.8 Faris Pawan (Pavia)
  Long-term plasticity in cerebellar microcircuit: preliminary findings and the role of clozapine
  
  P3.9 Giacomo Pennella (Florence)
  Monocular delay during active vision shifts ocular dominance
  
  P3.10 Chiara Penzo (Genoa)
  The epilepsy gene TBC1D24 regulates intra-organellar pH homeostasis in neurons and synapses
  
  P3.11 Natasha Petecca (Naples)
  Higher efficacy of 1,3-butanediol as a neuroprotective strategy in hippocampus of healthy rats compared to calorie restriction
  
  P3.12 Emiliana Piscitiello (Bologna)
  Synthetic torpor enhances resistance against radiation: transcriptome profiling of radioprotected livers
  
  P3.13 Amelia Pizzella (Naples)
  Altered synaptic plasticity in neurodevelopmental diseases: effect of 5-HT7R stimulation
  
  P3.14 Eleonora Poeta (Bologna)
  Angelman syndrome: a study on neuronal cultures derived from patients’ iPS cells
  
  P3.15 Elisa Principi (Ancona)
  Synaptic neurofilaments changes during aging and the effect of environmental enrichment
  
  P3.16 Alessandro Moscatelli (Rome)
  Motion of the touched surface alters the trajectory of hand movements in a reaching task
  
  P3.17 Raimondo Sollazzo (Rome)
  Neurons derived from sporadic Alzheimer’s disease hiPSCs reveal morphological and functional alterations associated with downregulation of LIMK1-cofilin axis
  
  P3.18 Surabhi Ramawat (Rome)
  Different neuronal cell types in the primate prefrontal cortex differently contribute to the rank-based information encoding
  
  P3.19 Ingrid Reverte Soler (Rome)
  Synaptic adaptations in the Nucleus Accumbens core and incubation of Meth craving after social choice-induced voluntary abstinence
  
  P3.20 Nicolò Ricciardi (Palermo)
  The remarkable impact of opuntia ficus indica fruit administration on metabolic syndrome: correlations between cognitive functions and oxidative stress in the high-fat, diet-fed rat model
  
  P3.21 Marco Rinaudo (Rome)
  Blood biomarkers predicting stress vulnerability
  
  P3.22 Anita Maria Rominto (Turin)
  Chronic social defeat stress increases prefrontal cortex excitability and Gsk3 activation in mice
  
  P3.23 Stefano Rozzi (Parma)
  Connectional organization reflect functional specificities of the different sectors of the macaque ventrolateral prefrontal cortex
  
  P3.24 Miriana Scordino (Palermo)
  Powerful protective and antioxidant effects of Grapefruit Integropectin on brain cells
  
  P3.25 Mariella Segreti (Rome)
  Ocular and neuronal responses to visual stimuli during free exploration of naturalistic videos in rhesus macaques
  
  P3.26 Franco Pio Siciliano (Rome)
  Does neuromuscular electrical stimulation influence spinal excitability in Multiple Sclerosis patients with spasticity?
  
  P3.27 Gianluca Signorile (Bari)
  New insights on the role of AQP4 and its isoforms in cerebral water homeostasis: an in vitro and in vivo study
  
  P3.28 Alessandro Silvani (Bologna)
  Initial preclinical development of a novel dual orexin receptor agonist
  
  P3.29 Jorge Storniolo (Milan)
  Postural assessment in a case of bilateral complete amputation of toes
  
  P3.30 Ludovico Taddei (Bologna)
  Synthetic torpor alleviates ischemia-reperfusion injury in Langendorff-perfused hearts
  
  P3.31 Tasnim Mohamed (Milan)
  Schwann cells acquire pro-inflammatory and migrating phenotype, influencing M2 macrophage polarization
  
  P3.32 Timna Hitrec (Bologna)
  A central neural network drives arousal from torpor in mice
  
  P3.33 Roberta Trovato (Catania)
  The upregulation of GLT-1 expression rescues synaptic plasticity and memory impairment in α7 nicotinic acetylcholine receptors knock out mice
  
  P3.34 Claudia Vitale (Florence)
  Role of Donepezil, a promising antitussive drug candidate, in the central regulation of the cough reflex in the rabbit 
  
  P3.35 Beatrice Zarrilli (Rome)
  Temporal development of functional alterations of midbrain dopaminergic neurons by transgenic expression of neuromelanin in a Parkinson’s disease mouse model
  
  P3.36 Giovanna Zoccoli (Bologna)
  Sleep fragmentation promotes neuronal loss in a mouse model of Down syndrome
  
  

  Physiology of Metabolism

  P3.37 Alessandra Adami (Kingston, USA)
  Association between muscle oxidative capacity and mortality in older individuals with and without COPD
  
  P3.38 Ines Angelini (Bari)
  Momast^® downregulates AQP3 expression and function in human colon cells
  
  P3.39 Sara Caputo (Rome)
  Neuroprotective mechanism(s) of neuroglobin involves the cholesterol metabolism
  
  P3.40 Ciro Menale (Naples)
  Nutrient availability regulation of osteoblasts function is associated with lipolysis modulation
  
  P3.41 Gianluca Fasciolo (Naples)
  Oxidative Stress effects on the hyperglycemia in the brain
  
  P3.42 Andrea Foppiani (Milan)
  Fasting metabolic flexibility and fat distribution
  
  P3.43 Antonia Giacco (Benevento)
  3,5-diiodo-L-thyronine (3,5-T2) reverted c-GAS/STING-mediated inflammation in a mouse model of NAFLD
  
  P3.44 Marta Giardina (Palermo)
  Impact of yellow prickly pear fruit on glucose metabolism in obese mice
  
  P3.45 Simona Lobasso (Bari)
  Wide variability in clinical features as a potential pitfall for the diagnosis of rare diseases: the case of  two cousins affected by molecularly confirmed Barth syndrome
  
  P3.46 Giuliana Panico (Naples)
  Effect of ketosis induced by 1,3-butanediol on brown adipose tissue functionality
  
  P3.47 Martina Parente (Rome)
  BET proteins as regulators of lysosomal cholesterol homeostasis in Niemann-Pick patients 
  
  P3.48 Giuseppe Scavo (Pesche)
  Disruption of cholesterol metabolism in Parkinson’s disease: a study on neuronal and glial cells
  
  P3.49 Simona Terzo (Palermo)
  Kumquat supplementation mitigates high-fat diet-induced neuronal impairment and Alzheimer's disease markers in obese mice
  
  P3.50 Giovanna Trinchese (Naples)
  Brain mitochondrial metabolism, neuroinflammation and synaptic plasticity are influenced by the dietary intake of milk in a rat model
  
  

  Cellular and Molecular Physiology

  P3.51 Pasquale Pagliaro (Orbassano)
  Cytoprotection by solidified xenon and antioxidant-loaded nanoparticle formulations
  
  P3.52 Francesco Palmieri (Florence)
  Mechano-mimetic substrates are a useful tool for early guidance of fibroblast-to-myofibroblast transition
  
  P3.53 Barbara Pavan (Ferrara)
  Chlorogenic acid permeation across intestinal cell monolayers: influence by circadian rhythms in the presence of other natural polyphenols and by dopaminergic neuronal-like cells
  
  P3.54 Luca Pipicelli (Naples)
  New mechanism of CuZn Superoxide Dismutase (SOD1) secretion via ATP-binding cassette (ABC) A1 transporter in Human T-lymphocytes
  
  P3.55 Rachele Prevostini (Monza)
  Characterization of an induced Pluripotent Stem Cell line derived from an individual affected by Developmental and Epileptic Encephalopathy carrying the HCN2 p.G460D variant
  
  P3.56 Alessia Remigante (Messina)
  Melatonin restores KV3.1/KCNC1 channel function in an oxidative stress-related model of cellular aging
  
  P3.57 Ivana Romano (Catania)
  Neural conditioned medium and melatonin effects on neural differentiation of human adipose-derived mesenchymal stem cells
  
  P3.58 Maria Rosito (Rome)
  Ketogenic diet induces an inflammatory reactive astrocytes phenotype reducing glioma growth
  
  P3.59 Giulia Rossi (Rome)
  Impact of the mutant form of Huntingtin protein on neuronal susceptibility to inflammatory stress
  
  P3.60 Federico Alessandro Ruffinatti (Turin)
  An omics insight into the expression of the ion transport toolkit in human cerebrovascular endothelial cells
  
  P3.61 Atiyehsadat Sharifzadeh (Milan)
  At the origin of congenital muscular dystrophy: shedding light on the Tdark proteins DPM2 and DPM3
  
  P3.62 Simona D'Aprile (Catania)
  Glioblastoma mesenchymal subtype tolerates ferroptosis through an increased antioxidant defense
  
  P3.63 Sara Spinelli (Messina)
  Exposure of human red blood cells to nano- and microplastics: mechanisms of internalization and evaluation of oxidative stress-related effects
  
  P3.64 Michela Terlizzi (Salerno)
  Sphingosine-1-phosphate signaling alters the physiological phenotype of circulating monocytes towards an immunosuppressive cluster
  
  P3.65 Filippo Torrisi (Enna)
  Evaluation of early physiopathological effects in mouse spinal cord neurons following proton irradiation
  
  P3.66 Nicola Zagaria (Bari)
  White blood cells AQP3 and AQP9 are involved in NLRP3 inflammasome activation and have relevance as prognostic biomarkers in sepsis
  
  P3.67 Rita Polito (Foggia)
  Synergistic Anti-Inflammatory Potential of Ketogenic Diet Components on CaCo-2 Cell Line